Polynucleotide treatments, sometimes referred to as PDRN (polydeoxyribonucleotide) therapies, are used in aesthetic medicine to support skin health and hydration. These treatments involve the use of highly purified polynucleotides—molecules originally derived from salmon DNA—to assist in improving skin texture and elasticity through regenerative processes.
These procedures are typically considered for individuals experiencing age-related skin changes, dryness, or reduced skin elasticity. Areas commonly discussed during consultation include the face, under-eye area, neck, and décolletage.
During the procedure, a series of superficial injections are administered to deliver polynucleotides into the skin. These molecules may assist with hydration and support the skin’s natural regenerative functions. Multiple sessions are often recommended for optimal effect, depending on individual skin condition and goals.
A consultation with a qualified medical practitioner is essential to determine suitability and develop a personalised treatment plan.
As with all injectable procedures, polynucleotide treatments carry potential risks and side effects. These may include:
Temporary redness, swelling, or bruising at the injection site
Mild itching, tenderness, or a warm sensation shortly after treatment
Rarely, small lumps or nodules under the skin
Infection or inflammation if proper technique is not followed
Although medical-grade products are highly purified, individuals with seafood allergies should disclose this during consultation, as caution may be advised.
More serious complications are uncommon but can occur. These procedures should only be performed by a qualified and experienced health professional.
Results vary between individuals, and no guarantees can be made regarding specific outcomes. A full medical consultation is required prior to treatment to assess suitability, provide informed consent, and ensure your medical history and skin concerns are thoroughly reviewed.